Top Proven HIV Prevention Strategies for 2025

By Health team 18 December, 2025

The battle against HIV/AIDS carries on with fresh energy, thanks to strides in medical science and public health tactics. A holistic approach to HIV prevention blends behavioral, biomedical, and structural strategies to address the varied needs of at-risk populations. Search now for tried-and-true HIV prevention methods:

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1. Pre-Exposure Prophylaxis (PrEP)
PrEP remains a cornerstone of HIV prevention strategies. This preventive treatment is recommended for individuals at high risk of HIV infection. By taking PrEP daily, one can significantly reduce the risk of getting HIV from sex or injection drug use. Two medications widely used for PrEP include:
Truvada is for all people at risk through sex or injection drug use.
Descovy is for sexually active men and transgender women at risk, although it's not approved for those at risk through vaginal sex, as more studies are needed in this area.

2. Consistent and Correct Condom Use
The use of condoms during all sexual encounters significantly reduces the risk of acquiring HIV, as well as other sexually transmitted infections (STIs). Condoms are highly effective when used consistently and correctly and are a key component of a comprehensive prevention strategy.

3. Treatment as Prevention (TasP)
For people living with HIV, achieving and maintaining an undetectable viral load through ART not only preserves their health but also prevents sexual transmission of the virus to an HIV-negative partner. This approach, known as "Undetectable = Untransmittable" (U=U), highlights the importance of:
Biktarvy, a single-tablet ART regimen that combines bictegravir, emtricitabine, and tenofovir alafenamide. It's designed for the treatment of HIV-1 infection and has shown high efficacy in reducing viral load to undetectable levels.

4. Post-Exposure Prophylaxis (PEP)
PEP is an emergency HIV prevention strategy used after potential exposure to the virus. It involves taking antiretroviral medicines within 72 hours after a possible exposure to prevent the virus from establishing an infection. PEP is recommended following unprotected sex, needle-sharing, or other exposure to HIV-infected fluids.

5. Regular HIV Testing and Counseling
Regular HIV testing is crucial for everyone, particularly those at high risk. Early detection of HIV status allows individuals to take appropriate steps to protect their health and prevent transmission to others. Counseling provides essential support and information on preventing HIV and living with the virus.

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